Polynucleotides work differently to dermal fillers or skin boosters. Rather than simply adding volume or hydration, they kickstart your skin’s own repair processes from within — encouraging genuine tissue regeneration and supporting your natural collagen and elastin production. The result is an improvement in skin quality that builds gradually and looks completely natural, rather than sitting on the surface.
It’s a genuinely versatile treatment, commonly used to plump fine lines and wrinkles, tighten and tone the skin, treat hollowing, and brighten dark circles — making it a popular choice for the delicate under-eye area as well as the wider face.
Not sure whether this is the right fit for your skin? Book in for a consultation and we’ll go through your concerns properly together, building a plan around what your skin actually needs.
Improved hydration & skin firmness.
Minimal to none
Up to 12-18 months.
30 minutes
Start by reaching out to talk through what's bothering you and what you'd like to achieve. You'll hear back from me personally, not a booking team, and I'll walk you through your options so you know exactly what's suited to your needs. Any questions along the way are always welcome, and you'll get straightforward, professional advice throughout.
Your consultation is a proper, unhurried face-to-face — never rushed, never a tick-box exercise. Together we'll cover your medical history, discuss what's concerning you and what result you're after, and I'll confirm you're a good candidate before we plan anything further. Getting you a safe, natural outcome that actually suits you is what matters most.
Every treatment is delivered across my salon and clinics with the same care, precision and attention to detail. My background combines Registered NMC Nurse Prescriber training with real NHS surgical experience, so you're getting genuine clinical skill. I'll always talk you through what to expect first, working in a relaxed setting that puts your comfort and natural-looking results front and centre.
Your care continues well after you leave. You'll be given clear aftercare instructions, and if anything crops up — a worry, something that feels off or anything else — you can reach me directly, no middleman. I'll also follow up to check how things are progressing and that you're happy with the outcome, because your wellbeing matters to me long after the appointment ends.
Start by reaching out to talk through what's bothering you and what you'd like to achieve. You'll hear back from me personally, not a booking team, and I'll walk you through your options so you know exactly what's suited to your needs. Any questions along the way are always welcome, and you'll get straightforward, professional advice throughout.
Your consultation is a proper, unhurried face-to-face — never rushed, never a tick-box exercise. Together we'll cover your medical history, discuss what's concerning you and what result you're after, and I'll confirm you're a good candidate before we plan anything further. Getting you a safe, natural outcome that actually suits you is what matters most.
Every treatment is delivered across my salon and clinics with the same care, precision and attention to detail. My background combines Registered NMC Nurse Prescriber training with real NHS surgical experience, so you're getting genuine clinical skill. I'll always talk you through what to expect first, working in a relaxed setting that puts your comfort and natural-looking results front and centre.
Your care continues well after you leave. You'll be given clear aftercare instructions, and if anything crops up — a worry, something that feels off or anything else — you can reach me directly, no middleman. I'll also follow up to check how things are progressing and that you're happy with the outcome, because your wellbeing matters to me long after the appointment ends.
Message from Helen Jackson
What matters most to me is that every client walks away looking like themselves, only more confident – that’s always been the goal. I bring the same medical rigour to every appointment that comes from years as an Advanced Nurse Practitioner and Prescriber, combined with a genuine passion for helping people feel confident in their own skin. My priority has always been subtle, natural-looking results delivered in a calm, welcoming environment, so you walk away feeling looked after, valued and glowing – inside and out. Helping people regain their confidence isn’t just my job, it’s what I love to do.
Helen Jackson
Advanced Nurse Practitioner and Prescriber
Polynucleotides are a regenerative injectable treatment that works by prompting your skin’s own natural repair processes into action. Rather than simply sitting within the skin, they actively encourage your body to boost collagen and elastin production, improve hydration, and support genuine tissue regeneration from within — giving results that build gradually and look entirely natural.
Skin boosters mainly work on hydration — plumping and refreshing the surface of the skin. Polynucleotides take a different approach entirely, focusing on genuine repair and regeneration rather than just moisture. They work to strengthen the skin from within, support its natural healing process, and stimulate your own collagen production — making them a stronger option if you’re after long-term rejuvenation rather than a quick hydration top-up.
Yes — polynucleotides aren’t just for the skin. They’re also used in scalp treatments to support hair regrowth and improve overall scalp health, working in a similar way by encouraging your body’s own repair processes. If hair thinning or loss is a concern for you, take a look at the dedicated Hair Loss page for more detail, or mention it at your consultation so we can build it into your treatment plan.
Polynucleotides address a genuinely wide range of concerns — fine lines, sagging or lax skin, dehydration, dullness, crepiness, dark circles, scarring, and general skin quality that’s lost its bounce. They’re particularly well suited to the delicate under-eye area, where skin tends to be thinner and shows early signs of ageing first. If you’re looking for rejuvenation that goes beyond a temporary refresh — genuinely improving the strength and health of your skin from within, rather than just how it looks on the day — this is a treatment worth considering. It’s also a popular option for anyone who’s tried other treatments without seeing the long-term improvement in skin quality they were hoping for.
Depending on the treatment area and what your skin needs, polynucleotides can be given using either a fine mesotherapy needle technique or a cannula. Which method’s most suitable for you will be discussed properly at your consultation, and built into your overall treatment plan.
Appointments typically take about 30–45 minutes altogether, covering your consultation, prep and the treatment itself — so there’s no rush and time is built in for everything.
This comes down to your individual concerns and what you’re hoping to achieve, but polynucleotides are generally most effective given as a course — usually around three sessions, spaced a few weeks apart — followed by occasional maintenance appointments to keep your results looking their best over time.
A good number of clients pick up on improvements to hydration and overall skin quality within the first few weeks. That said, since polynucleotides work by triggering your skin’s own regeneration process, the full benefits tend to develop gradually over several weeks and months, rather than showing up all at once.
Downtime is generally minimal. It’s normal to see some mild redness, swelling, tenderness or small bumps around the injection points, but this is expected and usually settles on its own within a few hours to a few days.
Absolutely — polynucleotides aren’t about adding volume or altering your features in any way. Their whole purpose is improving the health and quality of your skin from the inside out, so you’re left looking refreshed, rejuvenated and naturally radiant — simply a genuinely healthier version of your own skin.
A little groundwork ahead of time genuinely pays off — both for how comfortable your appointment feels and the results you’ll get. Take a moment to read through this before coming in.
Above everything else, I want your appointment to feel relaxed, genuinely high-end and welcoming — leaving you fully informed, at ease and confident in what comes next.
How your skin does after treatment comes down a lot to how you look after it in the days that follow, so here’s what to stick to after your polynucleotide treatment.
What I want, above all, is for you to end up with skin that’s genuinely healthier, stronger and naturally rejuvenated — and to feel properly looked after throughout the whole process.
